Have you been tested for food allergies? There is new research(2014) indicating that there are those who react to gluten, but yet, test negative for celiac disease. I ask because I used to be on meds for depression & irritability. I also have horrible short term memory, as well as being trach'd for chronic airway inflammation. Its driven me onto disability assistance. Struggled terribly with mood swings since i can remember(10 years old). Drs called it Bi-Polar. So, this past year, on my own, I decided to try a gluten free diet. Within the first week, I knew I was onto something. In four months, I was down 20 lbs and depression & irritability are much improved. As I researched the gluten symptoms, all of mine were found there, including airway issues. I'm a 55 yr. Old male and just now discovered this, on my own. Im now, a firm believer that any mental difficulties should first be treated by ruling out food allergies & sensitivities. Good Luck.